ODX Articles

Inflammation: A focus on cytokines - Part 1

Inflammation: A focus on cytokines Part 1 Dicken Weatherby, N.D. and Beth Ellen DiLuglio, MS, RDN, LDN Cytokines are basically messengers that facilitate immune function and take part in pro-inflammatory, anti-inflammatory, and allergic responses. [1]

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January 15, 2021

Inflammation - The Fire Inside Part 2

Inflammation and aging combine to create “inflammaging.” Dicken Weatherby, N.D. and Beth Ellen DiLuglio, MS, RDN, LDN Aging has been associated with a perpetual inflammatory cascade that involves IL-1alpha, IL-6, and NF-kappa B. Inflammaging refers to chronic low-grade systemic inflammation associated with aging but not caused by an infectious agent.

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January 14, 2021

Inflammation - The Fire Inside Part 1

Inflammation the fire inside: Overview Dicken Weatherby, N.D. and Beth Ellen DiLuglio, MS, RDN, LDN Inflammation refers to signs, symptoms, and cellular actions that occur in a complex response to infection, injury, trauma, overuse, toxins, or radiation exposure. Technically inflammation is a is a defense mechanism.[1]

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January 14, 2021

A Deeper Dive Into B12 - Part 4

How to correct B12 deficiency, choosing the right type of B12, dosage, food sources, etc. Dicken Weatherby, N.D. and Beth Ellen DiLuglio, MS, RDN, LDN Is the current RDA enough? The RDA Dietary Reference Intake (DRI) for vitamin B12 is 2.4 ug/day for non-pregnant, non-lactating adults.[1]

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December 2, 2020

A Deeper Dive Into B12 - Part 3

Biomarkers and how we can assess for B12 deficiency Dicken Weatherby, N.D. and Beth Ellen DiLuglio, MS, RDN, LDN A full clinical assessment of B12 status includes review of signs and symptoms as well as extended blood chemistry analysis. Assessment of B12 status can be complex because: [1]

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December 1, 2020

A Deeper Dive Into B12 - Part 2

The road to B12 deficiency and what happens when we get there… Dicken Weatherby, N.D. and Beth Ellen DiLuglio, MS, RDN, LDN Elderly status, strict vegetarianism, and lack of intrinsic factor have been traditionally recognized as the main causes of B12 deficiency.[1]

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November 30, 2020

A Deeper Dive Into B12 - Part 1

Vitamin B12 Biochemistry and Physiology Dicken Weatherby, N.D. and Beth Ellen DiLuglio, MS, RDN, LDN Vitamin B12, a cobalt-containing compound known as cobalamin, is synthesized by bacteria yet essential to humans. The term cobalamin is a generic term for corrinoids (containing a corrin nucleus).[1]

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November 28, 2020

QUICKI

QUICKI – An Additional Index for Assessing Insulin Resistance in Our Patients Dicken Weatherby, N.D. and Beth Ellen DiLuglio, MS, RDN, LDN QUICKI (Quantitative Insulin Sensitivity Check Index), a variation of HOMA2, is a simple calculation that uses fasting glucose and fasting insulin to assess insulin sensitivity and show the degree of insulin resistance.

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November 9, 2020

HOMA2 - %IR

HOMA2 - IR: An Index For Assessing the Degree of Insulin Resistance Dicken Weatherby, N.D. and Beth Ellen DiLuglio, MS, RDN, LDN Insulin resistance is a term used to indicate the failure of the peripheral tissue cells to respond appropriately to insulin, therefore impairing their capacity to uptake glucose from the blood stream, and resulting in an increased serum blood glucose level. 

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November 8, 2020

HOMA2 - %B

HOMA2 - %B: An Index For Gauging the Beta Cell Output of Insulin from the Pancreas Dicken Weatherby, N.D. and Beth Ellen DiLuglio, MS, RDN, LDN The beta cells of the pancreatic islets are responsible for production and secretion of insulin. Beta cells have a small capacity to store insulin, and the stored insulin is secreted immediately upon elevation of blood glucose levels, causing a resultant short-term increase in blood insulin levels.

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November 8, 2020

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