Vitamin D Update

Optimal - The Podcast: Episode 4 - Part 2 Vitamin D Update

Dr. Dicken Weatherby & Beth Ellen DiLuglio

Welcome to episode 4 of "Optimal - The Podcast" recorded May 13th, 2020. In part 2 we cover an update on Vitamin D.

Dr. Michael Holick, Ph.D., M.D. Professor of Medicine, Physiology and Biophysics; Director of the General Clinical Research Unit; and Director of the Bone Health Care Clinic and the Director of the Heliotherapy, Light, and Skin Research Center at Boston University Medical Center. Dr. Holick believes that maintaining a level of 40 to 60 ng/ml is desirable in the general population and a level up to 100 ng/ml is “perfectly safe.” [Vitamin D Society]

Others urge caution about going above 50 ng/ml. “The data are not clear cut, but some evidence of toxicity has been associated with levels above 50 ng/ ml, including hypercalcemia and kidney stones,” says Clifford Rosen, MD, director of clinical and translational research at the Maine Medical Center Research Institute, who worked on the IOM guideline.

Research Studies and Links

Ilie PC, Stefanescu S, Smith L. The role of vitamin D in the prevention of coronavirus disease 2019 infection and mortality. Aging Clin Exp Res. 2020 May 6. [R]

Fang et al. Online Mar 11 2020 The Lancet RespMed [R]

Bischoff-Ferrari HA. Optimal serum 25-hydroxyvitamin D levels for multiple health outcomes. Adv Exp Med Biol. 2008;624:55-71. [R]

Sadat-Ali M, Al-Anii FM, Al-Turki HA, et al. Maintenance Dose of Vitamin D: How Much Is Enough? J Bone Metab. 2018 Aug;25(3):161-164. [R]

Vitamin D Society [R]

Just Right: How Much Vitamin D is Enough? BY ERIC SEABORG NOV 2014 [R]

Manson JE, Cook NR, Lee IM, et al; VITAL Research Group. Vitamin D Supplements and Prevention of Cancer and Cardiovascular Disease. N Engl J Med. 2019 Jan 3;380(1):33-44. [R]

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