Optimal - The Blog

November 18, 2022

Lipoprotein "Little a" is a Big Deal

Lipoprotein (a) is a highly atherogenic lipoprotein consisting of an Apo A and an Apo B molecule bound together. It can become oxidized, damage the inside of blood vessels, and increase risk of atherosclerosis, major adverse cardiovascular events, and cerebrovascular disease. 

Elevated Lp(a) is associated with heart disease, hypothyroidism, diabetes, renal failure, and estrogen depletion. Low levels may be seen with malnutrition, liver disease, and alcoholism.

Although levels of Lp(a) have a strong genetic component, research suggests that a healthy plant-based diet and lifestyle can reduce levels.

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Tag(s): Biomarkers

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