Oxidized low-density lipoprotein (oxLDL) results from LDL undergoing oxidative modification, and its presence can drive atherosclerosis development due to its pro-inflammatory properties and contribution to endothelial damage.
This oxidized form of LDL is associated with numerous health problems, including coronary artery disease, obesity, metabolic syndrome, hypothyroidism, and heightened cardiometabolic risk.
Key factors like smaller LDL particles are more susceptible to oxidation but can be combated through dietary adjustments such as increasing antioxidant-rich food and omega-3 fatty acids intake.
Overall, monitoring oxLDL levels is vital in assessing cardiometabolic risk since it indicates not only current oxidative stress but also exacerbates it by activating certain immune cells, fostering atherosclerosis.
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