Optimal - The Podcast: Episode 6

Optimal - The Podcast: Episode 6

Dr. Dicken Weatherby & Beth Ellen DiLuglio, MS, RDN, LDN

Welcome to episode 6 of "Optimal - The Podcast" recorded July 10th, 2020.

Here's a breakdown of what we covered and timing:

Introduction (00:00:00)
Personal COVID-19 Update (00:02:59)
Oxidative Stress – Intro (00:07:17)
Glutathione, Oxidative Stress & COVID-19 (00:17:07)
Oxidative Stress – Biomarkers (00:30:43)
New Ask Me Anything (AMA) Feature (00:34:15)
AMA Q1 - What if a patient is close to being outside the functional range how would you interpret that pattern? (00:35:00)
AMA Q2 - What is the time frame that you would consider blood test results clinically relevant? (00:37:57)
AMA Q3 - I get quite a few patients coming with blood work from other doctors and there are often very few biomarkers on these panels compared to what you recommend. How do I use the software for this? (00:41:31)
AMA Q4 - If someone has high amylase and lipase in their blood results - what can this mean? (00:46:15)
AMA Q5 - Will eosinophils be elevated with an H.Pylori infection? (00:50:35)
ODX Biomarkers – Adiponectin (00:52:32)
ODX Biomarkers – Active B12 (01:00:11)
ODX Biomarkers – Selenium (01:05:32)
ODX Biomarkers – Free T3:Free T4 Ratio (01:09:50)

Research Studies and Links

Correlation between Oxidative Stress, Nutrition, and Cancer Initiation

oxidative_stress

Saha, Subbroto Kumar et al. “Correlation between Oxidative Stress, Nutrition, and Cancer Initiation.” International journal of molecular sciences vol. 18,7 1544. 17 Jul. 2017,  [R]

Glutathione

Nutrients and plant-based compounds support glutathione production and activity
Minich, Deanna M, and Benjamin I Brown. “A Review of Dietary (Phyto)Nutrients for Glutathione Support.” Nutrients vol. 11,9 2073. 3 Sep. 2019, [R]

Dr. Pizzorno’s review article on Glutathione

Pizzorno, Joseph. “Glutathione!.” Integrative medicine (Encinitas, Calif.) vol. 13,1 (2014): 8-12. [R] 

Glutathione, oxidative stress, and COVID-19

glutathione_oxidative_stress

Polonikov, Alexey. “Endogenous Deficiency of Glutathione as the Most Likely Cause of Serious Manifestations and Death in COVID-19 Patients.” ACS infectious diseases, acsinfecdis.0c00288. 28 May. 2020 [R]

Additional Oxidative Stress Information

Cholesterol acts as an antioxidant
Butterfield, J D Jr, and C P McGraw. “Free radical pathology.” Stroke vol. 9,5 (1978): 443-5. [R]

Smith, L L. “Another cholesterol hypothesis: cholesterol as antioxidant.” Free radical biology & medicine vol. 11,1 (1991): 47-61. [R]

ODX Biomarker Articles

 

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