Optimal - The Blog

August 20, 2020

Optimal - The Podcast: Episode 1

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Optimal - The Podcast: Episode 1 Oxidative Stress

Dr. Dicken Weatherby & Beth Ellen DiLuglio, MS, RDN, LDN

Welcome to episode 1 of "Optimal - The Podcast". In today's episode we cover Oxidative Stress and a number of new and interesting biomarkers that have been added into the ODX Software application.

Here's a breakdown of what we covered and timing:

Introduction (00:00:00)
Personal COVID-19 Update (00:02:59)
Oxidative Stress – Intro (00:07:17)
Glutathione, Oxidative Stress & COVID-19 (00:17:07)
Oxidative Stress – Biomarkers (00:30:43)
ODX Biomarkers – Adiponectin (00:52:32)
ODX Biomarkers – Active B12 (01:00:11)
ODX Biomarkers – Selenium (01:05:32)
ODX Biomarkers – Free T3:Free T4 Ratio (01:09:50)

The ODX Oxidative Stress Series

  1. Oxidative Stress part 1 - And You Thought You Were Stressed!
  2. Oxidative Stress part 2 - Blood Biomarkers: Functional Blood Chemistry Clues
  3. Oxidative Stress part 3 - Specialized Markers Provide More Clues
  4. Oxidative Stress part 4 - Cardiometabolic Disease & Oxidative Stress
  5. Oxidative Stress part 5 - The Cholesterol Connection
  6. Oxidative Stress part 6 - Glutathione Inside and Out

Research Studies and Links

Correlation between Oxidative Stress, Nutrition, and Cancer Initiation


Saha, Subbroto Kumar et al. “Correlation between Oxidative Stress, Nutrition, and Cancer Initiation.” International journal of molecular sciences vol. 18,7 1544. 17 Jul. 2017,  [R]


Nutrients and plant-based compounds support glutathione production and activity
Minich, Deanna M, and Benjamin I Brown. “A Review of Dietary (Phyto)Nutrients for Glutathione Support.” Nutrients vol. 11,9 2073. 3 Sep. 2019, [R]

Dr. Pizzorno’s review article on Glutathione

Pizzorno, Joseph. “Glutathione!.” Integrative medicine (Encinitas, Calif.) vol. 13,1 (2014): 8-12. [R] 

Glutathione, oxidative stress, and COVID-19


Polonikov, Alexey. “Endogenous Deficiency of Glutathione as the Most Likely Cause of Serious Manifestations and Death in COVID-19 Patients.” ACS infectious diseases, acsinfecdis.0c00288. 28 May. 2020 [R]

Additional Oxidative Stress Information

Cholesterol acts as an antioxidant
Butterfield, J D Jr, and C P McGraw. “Free radical pathology.” Stroke vol. 9,5 (1978): 443-5. [R]

Smith, L L. “Another cholesterol hypothesis: cholesterol as antioxidant.” Free radical biology & medicine vol. 11,1 (1991): 47-61. [R]

ODX Biomarker Articles

Tag(s): Podcast

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