Optimal - The Blog

August 1, 2022

Luteinizing Hormone: A Busy Hormone in Women

Luteinizing hormone (LH) is produced by the pituitary gland and plays important roles in ovulation, fertility, and the regulation of estrogen in women. Blood levels of LH will surge 24 hours before ovulation, a time when fertility peaks. In addition to ovulation, LH supports egg implantation and menstrual cycle regulation.

Low levels in the blood can occur with stress, malnutrition, calorie deficit, pesticide exposure, and certain medications including oral contraceptives.

Higher blood levels are associated with menopause, polycystic ovaries, amenorrhea, pituitary tumors, and certain medications. Higher blood levels may be associated with lower brain levels, which can negatively affect memory and cognition. Research suggests that reducing the surge in serum LH that occurs with menopause may help normalize brain LH and improve cognition.

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Tag(s): Biomarkers

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