Optimal - The Blog
November 8, 2022
Although it sounds like a mouthful, the estimated glomerular filtration rate (eGFR) is simply a way to evaluate how well your kidneys are filtering toxins, particularly creatinine. Creatinine is a byproduct of muscle metabolism that can become toxic if it builds up, so it must be excreted by the kidneys.
Estimating GFR is a convenient and efficient way to assess kidney function without requiring a 24-hour urine collection. The eGFR calculation usually incorporates age, gender, and creatinine to account for the expected decline in kidney function that comes with aging.
A low eGFR is associated with impairment of kidney function, liver cirrhosis, congestive heart failure, and dehydration. A high eGFR can be seen in high-output cardiac syndromes, exercise, and pregnancy.
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Biomarkers
