Eosinophils Can Defend and Destruct

Eosinophils, a subset of white blood cells, play a pivotal role in immune responses, particularly against allergies, asthma, and parasitic infections, while also helping maintain immune balance. However, an elevated eosinophil count can lead to tissue damage and disrupt homeostasis.

While primarily known for their role in parasitic infections and type-II immune responses, eosinophils also influence many physiological processes, including metabolism, glucose homeostasis, and tissue repair. 

High eosinophil counts are associated with allergies, asthma, autoimmune diseases, some cancers, and metabolic syndrome, while low counts are seen with corticosteroid therapy, Cushing’s disease, acute bacterial infections, and most viral infections.

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