Author Archives: Dr. Dicken Weatherby

Beyond PSA - Additional Biomarkers for Assessing Prostate Function

In my previous article on assessing prostate function I talked about the crucial role that prostate-specific antigen (PSA) plays in men’s health. However, PSA levels alone aren’t enough to diagnose prostate cancer, which is why I want to talk about other primary biomarkers for prostate cancer that we need to consider.

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August 3, 2020

Why Prostate-Specific Antigen Is a Key Biomarker for Men

Compared to testosterone, it can be easy to forget about the crucial role that prostate-specific antigen (PSA) plays in men’s health. However, this biomarker’s levels in the blood serve as one of functional medicine practitioners’ most important tools for ensuring the health of their male patients.

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July 31, 2020

Blood Chemistry Analysis and Functional Medicine: What You Need to Know

It’s tempting to consider blood chemistry analysis as a diagnostic practice that falls squarely in the domain of allopathic medicine. Anyone who has ordered or had a blood test knows that the results are typically a battery of individual markers, measurements and statistical ranges that offer very little insight into the functional health of the testee. Blood tests — as many Functional Medicine practitioners believe — are only useful for diagnosing patients already presenting with severe illness.

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July 27, 2020

AMA Archive

AMA Episodes Dr. Dicken Weatherby and Beth Ellen DiLuglio, MS, RDN, LDN This is the archive of all the "Ask Me Anything" (AMA) episodes we have recorded. Active software users get to ask clinical questions and we answer them on a monthly basis and post the answers to this archive page as well as the individual episode pages, which are linked below.

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July 22, 2020

AMA Episode 2

Welcome to AMA episode 2. In this episode Dicken and Beth Ellen answer a number of questions submitted by the ODX software users including looking at guidelines about how long a patient should stop supplementation prior to re-testing, the rationale behind WBC % reading in relation to WBC absolutes, weird prolactin units, GlycA as an inflammatory biomarker, and what are some of the other reasons for an elevated RBC, HCT and HGB other than dehydration.

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July 22, 2020

AMA Episode 1

Welcome to episode 1 of our new "Ask Me Anything" (AMA) feature. In this episode Dicken and Beth Ellen look at the best ways to handle biomarkers that are close to the optimal range and how to handle blood test results that are brought in that are a few months old.

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July 19, 2020

COVID-19, Zinc Deficiency and the Zinc Taste Test

I’ve been reading more and more recently, as I am sure have you, about the connection between a loss of taste and smell and Covid-19, the disease caused by an infection of the SARS-CoV-2 virus.

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April 9, 2020

Supporting Optimal Immune Function During the Covid-19 Crisis

  Treating Immune Dysfunction At Optimal DX, our mission is to help you help your patients achieve optimal health so they can experience an optimal life. We remain steadfast in our commitment to creating cutting-edge tools for you to offer a clear view of each person's health and better define how their health can be improved. 

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April 8, 2020

Free T3 : Reverse T3 Ratio

Free T3:Reverse T3 Ratio – an interview with Dr. Shawn Soszka, Naturopathic Physician and Acupuncturist Dr. Shawn Soszka is a Naturopathic Physician and acupuncturist practicing in Portland, OR. He is the author of “The Thyroid Fix” and an expert in …

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April 2, 2020

Know Your Biomarkers: Apolipoproteins

Apoliporoteins – Apo A-1, Apo B, & Lipoprotein (a) Today we are going to talk about Apolipoproteins and their role in uncovering trends towards cardiovascular disease. In order to understand what Apolipoproteins are, we need to go back to the …

  Apoliporoteins – Apo A-1, Apo B, & Lipoprotein (a)   Today we are going to talk about Apolipoproteins and their role in uncovering trends towards cardiovascular disease. In order to understand what Apolipoproteins are, we need to go back to the cholesterol molecule itself. Cholesterol is a hydrophobic or “water-repelling” molecule and therefore needs a protein transporter molecule to move in the blood. These proteins are called apoproteins. Once bound to lipids these apoproteins are called apolipoproteins and that is what we are able to measure in the blood. The whole package or “vehicle” that carries the cholesterol (and the apolipoprotein, the phospholipid, and the triglyceride), is called a Lipoprotein.   The apolipoproteins themselves are found on the surface of the lipoprotein and help hold the lipoprotein together. The major lipoproteins are Low-Density Lipoprotein, the familiar LDL and High-Density Lipoprotein commonly known as HDL. Apolipoproteins come in different shapes and sizes. Two of the most important ones are : Apolipoprotein A-1 (Apo-A1) and Apolipoprotein-B (Apo-B) Most Apo-A1 is found on High-Density Lipoproteins – HDL and the majority of Apo-B is found on Low-Density Lipoproteins – LDL Apo-A1 Apolipoprotein A-1 represents 60-70% of the protein content of HDL and plays a crucial role in transporting cholesterol from peripheral tissues to the liver for processing and degradation.Evaluation of Apo A-1 levels can help determine cardiovascular risk in those with reduced levels of HDL, increased cholesterol and triglycerides, and those with a family history of cardiovascular disease. Elevated levels of Apo-A1 are considered protective against cardiovascular disease and are believed to be a greater predictor for a lower incidence of cardiovascular disease than HDL alone. Low levels of Apo-A1 are associated with an increased risk of cardiovascular disease. Apo-B Apolipoprotein B facilitates the transport of lipids through the bloodstream. Apo-B combines with dietary lipids to form the triglyceride-rich lipoprotein called VLDL Over time as it travels through the blood, VLDL “drops off” its triglyceride content to become the cholesterol-rich lipoprotein known as LDL. Apo B levels tend to mirror LDL levels so will be elevated when LDL cholesterol is elevated. Evaluation of Apo-B levels can help assess cardiovascular risk and factors underlying elevated triglycerides. Elevated Apo-B corresponds to elevated LDL and non-HDL cholesterol with an associated increased risk of cardiovascular disease and an associated increased risk of atherosclerotic coronary artery diseaseSome would suggest that Apo- A1 and Apo-B are much better markers for cardiovascular disease than traditional lipid studies. Lipoprotein (a) For the sake of completion, I want to cover a 3rd lipid marker called Lipoprotein (a) or Lp (a). Lipoprotein (a) or Lp (a) is a small dense lipoprotein composed of a low-density lipoprotein particle and one apolipoprotein B100 molecule linked by a disulfide bond to apolipoprotein(a). Excess Lp(a) is associated with an increased risk of cardiac death in those with coronary artery disease and stroke and increased blood levels of Lp(a) may be a strong independent risk factor for atherosclerosis and early cardiovascular disease. All 3 of these biomarkers are now available in the ODX Application so go ahead, measure them in your patients and add them to their Functional Health Report!

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June 14, 2019

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FBCA Mastery Training 2020

The next enrolment of Dr. Weatherby’s “FBCA Mastery Certification Training” opens September 23rd, 2020


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