Progesterone, derived from cholesterol, is vital for various physiological functions, including reproduction, bone health, and cardiovascular health. In menopause, it helps manage symptoms like hot flashes, night sweats, and sleep disturbances.
However, elevated levels in postmenopausal women are linked to prediabetes, type 2 diabetes, and certain ovarian tumors. While natural progesterone is preferred for hormone replacement therapy and often applied transdermally, its impact on cognition during postmenopause remains inconclusive.
Research also indicates progesterone can reduce alcohol cravings in postmenopausal women with alcohol use disorder.
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